bio325 guest lectures

Guest lectures in Evolution in Action, BIO325, Spelman College, Spring 2016, 

March 31 Thu, 

1. Install R and RStudio. 
Step1:   Instructions to download R. 
Step2:   Install R studio.  For more information, see 
http://hongqinlab.blogspot.com/2015/01/rrstudio-tutorial-page-for-bio125.html

2. Download computer exercises codes and files
https://github.com/hongqin/bio325.sp16


3. Microarray and gene expression profiling  

https://en.wikipedia.org/wiki/DNA_microarray

https://en.wikipedia.org/wiki/Gene_expression_profiling

https://en.wikipedia.org/wiki/Hierarchical_clustering

4.  Clustering demo using a picture (Student group exercise)
Reshuffle pixels in a picture to demonstrate the utility of clustering.

Students will need to install HeatPlus, adimpro, and pixmap packages. 

April 5 Tue

5. Data analysis exercise
Expression data from S. cerevisiae under serial stresses, including H2O2 time course

Reference:  http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE15936
 http://www.ncbi.nlm.nih.gov/pubmed/19536156